This is a catalogue of the Edward C. Atwater collection of rare books dealing with 'popular medicine' in early American which is housed at the University of Rochester Medical School library. The books described in the catalogue were written by physicians and other professionals to provide information for the non-medical audience. The books taught human anatomy, hygiene, temperance and diet, how to maintain health, and how to cope with illness especially when no professional help was available. The books promoted a healthy lifestyle for the readers, giving guidance on everything from physical fitness and recreation to the special health needs of women. The collection consists of works dealing with reproduction (from birth control to delivering and caring for a baby), venereal disease, home-nursing, epidemics, and the need for public sex education. These books, covering areas largely ignored by the medical profession, made important contributions to the health of the American public, and the collection is a vital piece of medical history. The collector is Edward C. Atwater, professor emeritus of medicine and the history of medicine at the University of Rochester Medical School. Christopher Hoolihan is History of Medicine Librarian at the University of Rochester Medical School's Edward G. Miner Library.